Tetramatrix™ is a biostealth fluid technology, engineered to transition at physiological temperature and form a tissue-adhering 3D matrix after delivery. Designed as a single platform that can be adapted into distinct derivatives for different tissues, indications, and delivery requirements, without reinventing the underlying system each time.
Application
Scroll down to view our franchises and products
Scroll down to view our franchises and products
Tetramatrix™ is a biostealth fluid technology, engineered to transition at physiological temperature and form a tissue-adhering 3D matrix after delivery. Designed as a single platform that can be adapted into distinct derivatives for different tissues, indications, and delivery requirements, without reinventing the underlying system each time.
Application
Scroll down to view our franchises and products
Scroll down to view our franchises and products
Tetramatrix™ is a biostealth fluid technology, engineered to transition at physiological temperature and form a tissue-adhering 3D matrix after delivery. Designed as a single platform that can be adapted into distinct derivatives for different tissues, indications, and delivery requirements, without reinventing the underlying system each time.
THE OVERVIEW
Application
Scroll down to view our franchises and products
Scroll down to view our franchises and products
Franchise 001 Bone Regeneration
Tegenix
A universal enabling solution to simplify complex oral & dental procedures. An innovative solution designed to be mixed with bone graft material or for dental and oral bone repair.
•
1. Mix and match carrier
A carrier system for bone graft materials to form mouldable and shapeable composites for easy and gentle delivery, which preserves the integrity of the host tissue for faster healing.
•
2. Simplifying Complex Procedures
A carrier system for bone graft materials to form mouldable and shapeable composites for easy and gentle delivery, which preserves the integrity of the host tissue for faster healing.
•
3. Supports Natural Healing
The matrix maintains the graft in 3D geometry to allow cellular ingrowth and integration within the composite. The biocompatible nature of the hydrogel works synergistically with the graft, supporting natural healing.
Franchise 001 Bone Regeneration
TegenEOS
TegenEOS mixes with human derived bone grafts to form flowable formulations with lower graft content; reducing the dependency on human donors while allowing novel minimally invasive applications in foot and ankle trauma and general orthopaedic surgeries.
•
1. Flowable Bone Graft Delivery
Once mixed with bone grafts, the resulting mixture is flowable for ease of delivery for trauma surgeries and other orthopaedic procedures.
•
2. 3D Graft Stabilisation and Activation
The bone grafts are kept in a 3D manner at the intended sites, allowing cellular ingrowth for a more effective cell-activation/ osteoinductivity, leading to faster healing.
•
3. Increased Yield. Higher Throughput
The carrier system reduces the requirement for the amount of bone grafts and thus increases production throughputs for the partners from defined number of human donors.
Franchise 001 Bone Regeneration
Tegenix
A universal enabling solution to simplify complex oral & dental procedures. An innovative solution designed to be mixed with bone graft material or for dental and oral bone repair.
•
1. Mix and match carrier
A carrier system for bone graft materials to form mouldable and shapeable composites for easy and gentle delivery, which preserves the integrity of the host tissue for faster healing.
•
2. Simplifying Complex Procedures
A carrier system for bone graft materials to form mouldable and shapeable composites for easy and gentle delivery, which preserves the integrity of the host tissue for faster healing.
•
3. Supports Natural Healing
The matrix maintains the graft in 3D geometry to allow cellular ingrowth and integration within the composite. The biocompatible nature of the hydrogel works synergistically with the graft, supporting natural healing.
Franchise 001 Bone Regeneration
TegenEOS
TegenEOS mixes with human derived bone grafts to form flowable formulations with lower graft content; reducing the dependency on human donors while allowing novel minimally invasive applications in foot and ankle trauma and general orthopaedic surgeries.
•
1. Flowable Bone Graft Delivery
Once mixed with bone grafts, the resulting mixture is flowable for ease of delivery for trauma surgeries and other orthopaedic procedures.
•
2. 3D Graft Stabilisation and Activation
The bone grafts are kept in a 3D manner at the intended sites, allowing cellular ingrowth for a more effective cell-activation/ osteoinductivity, leading to faster healing.
•
3. Increased Yield. Higher Throughput
The carrier system reduces the requirement for the amount of bone grafts and thus increases production throughputs for the partners from defined number of human donors.
Franchise 001 Bone Regeneration
Tegenix
A universal enabling solution to simplify complex oral & dental procedures. An innovative solution designed to be mixed with bone graft material or for dental and oral bone repair.
•
1. Mix and match carrier
A carrier system for bone graft materials to form mouldable and shapeable composites for easy and gentle delivery, which preserves the integrity of the host tissue for faster healing.
•
2. Simplifying Complex Procedures
A carrier system for bone graft materials to form mouldable and shapeable composites for easy and gentle delivery, which preserves the integrity of the host tissue for faster healing.
•
3. Supports Natural Healing
The matrix maintains the graft in 3D geometry to allow cellular ingrowth and integration within the composite. The biocompatible nature of the hydrogel works synergistically with the graft, supporting natural healing.
Franchise 001 Bone Regeneration
TegenEOS
TegenEOS mixes with human derived bone grafts to form flowable formulations with lower graft content; reducing the dependency on human donors while allowing novel minimally invasive applications in foot and ankle trauma and general orthopaedic surgeries.
•
1. Flowable Bone Graft Delivery
Once mixed with bone grafts, the resulting mixture is flowable for ease of delivery for trauma surgeries and other orthopaedic procedures.
•
2. 3D Graft Stabilisation and Activation
The bone grafts are kept in a 3D manner at the intended sites, allowing cellular ingrowth for a more effective cell-activation/ osteoinductivity, leading to faster healing.
•
3. Increased Yield. Higher Throughput
The carrier system reduces the requirement for the amount of bone grafts and thus increases production throughputs for the partners from defined number of human donors.
Franchise 001 Bone Regeneration
Tegenix
A universal enabling solution to simplify complex oral & dental procedures. An innovative solution designed to be mixed with bone graft material or for dental and oral bone repair.
•
1. Mix and match carrier
A carrier system for bone graft materials to form mouldable and shapeable composites for easy and gentle delivery, which preserves the integrity of the host tissue for faster healing.
•
2. Simplifying Complex Procedures
A carrier system for bone graft materials to form mouldable and shapeable composites for easy and gentle delivery, which preserves the integrity of the host tissue for faster healing.
•
3. Supports Natural Healing
The matrix maintains the graft in 3D geometry to allow cellular ingrowth and integration within the composite. The biocompatible nature of the hydrogel works synergistically with the graft, supporting natural healing.
Franchise 001 Bone Regeneration
TegenEOS
TegenEOS mixes with human derived bone grafts to form flowable formulations with lower graft content; reducing the dependency on human donors while allowing novel minimally invasive applications in foot and ankle trauma and general orthopaedic surgeries.
•
1. Flowable Bone Graft Delivery
Once mixed with bone grafts, the resulting mixture is flowable for ease of delivery for trauma surgeries and other orthopaedic procedures.
•
2. 3D Graft Stabilisation and Activation
The bone grafts are kept in a 3D manner at the intended sites, allowing cellular ingrowth for a more effective cell-activation/ osteoinductivity, leading to faster healing.
•
3. Increased Yield. Higher Throughput
The carrier system reduces the requirement for the amount of bone grafts and thus increases production throughputs for the partners from defined number of human donors.
Franchise 001 Bone Regeneration
Tegenix
A universal enabling solution to simplify complex oral & dental procedures. An innovative solution designed to be mixed with bone graft material or for dental and oral bone repair.
•
1. Mix and match carrier
A carrier system for bone graft materials to form mouldable and shapeable composites for easy and gentle delivery, which preserves the integrity of the host tissue for faster healing.
•
2. Simplifying Complex Procedures
A carrier system for bone graft materials to form mouldable and shapeable composites for easy and gentle delivery, which preserves the integrity of the host tissue for faster healing.
•
3. Supports Natural Healing
The matrix maintains the graft in 3D geometry to allow cellular ingrowth and integration within the composite. The biocompatible nature of the hydrogel works synergistically with the graft, supporting natural healing.
Franchise 001 Bone Regeneration
TegenEOS
TegenEOS mixes with human derived bone grafts to form flowable formulations with lower graft content; reducing the dependency on human donors while allowing novel minimally invasive applications in foot and ankle trauma and general orthopaedic surgeries.
•
1. Flowable Bone Graft Delivery
Once mixed with bone grafts, the resulting mixture is flowable for ease of delivery for trauma surgeries and other orthopaedic procedures.
•
2. 3D Graft Stabilisation and Activation
The bone grafts are kept in a 3D manner at the intended sites, allowing cellular ingrowth for a more effective cell-activation/ osteoinductivity, leading to faster healing.
•
3. Increased Yield. Higher Throughput
The carrier system reduces the requirement for the amount of bone grafts and thus increases production throughputs for the partners from defined number of human donors.
Franchise 002 Tissue Spacing
Tutelix
Tutelix is intended for use as a spacer to reduce side effects to surrounding tissue during radiation therapy to treat prostate cancer. It is easily injected and is gradually resorbed by the body and excreted over time.
•
1. Procedure Optionality
Clinicians can apply it at their pace—no chemical cure, no time pressure—using one or multiple units as needed.
•
2. Stable and Simple to Adjust
The hydrogel is smooth, flowable and can be immediately reversed with cold-saline. The hydrogel is stable for 6 months and breaks down to non-toxic components and bioresorbs.
•
3. Visibility Drives Precise Radiotherapy
The hydrogel is visible during the surgery under ultrasound so clinicians can see where they are deploying the product. It remains visible and stable for accurate radiation therapy.
Franchise 002 Tissue Spacing
Optimatrix
Novel synthetic, reversible OVD for safe, simple application. Optimatrix is fully synthetic, preserves ocular volume and shape during surgery, and is removed easily with a cold saline wash. Cold‑saline dissolution prevents residue‑driven inflammation and cuts reliance on animal‑derived materials.
•
1. Ethical Supply Security
Fully synthetic with zero animal‑derived components, ensuring ethical sourcing and superior animal‑welfare credentials. That guarantees supply‑chain security for partners and removes ethical and regulatory exposure.
•
2. Scale Fast, Cut Costs
Low COGS, scalable production and tight sterility/endotoxin control deliver commercially compelling unit economics—reliable margins and predictable supply at scale.
•
3. Rapid Removal via Dissolution
Cold‑saline instantly dissolves the product, enabling fast, effortless removal right after surgery—no scraping, no residue, and minimal OR time.
Franchise 002 Tissue Spacing
Tutelix
Tutelix is intended for use as a spacer to reduce side effects to surrounding tissue during radiation therapy to treat prostate cancer. It is easily injected and is gradually resorbed by the body and excreted over time.
•
1. Procedure Optionality
Clinicians can apply it at their pace—no chemical cure, no time pressure—using one or multiple units as needed.
•
2. Stable and Simple to Adjust
The hydrogel is smooth, flowable and can be immediately reversed with cold-saline. The hydrogel is stable for 6 months and breaks down to non-toxic components and bioresorbs.
•
3. Visibility Drives Precise Radiotherapy
The hydrogel is visible during the surgery under ultrasound so clinicians can see where they are deploying the product. It remains visible and stable for accurate radiation therapy.
Franchise 002 Tissue Spacing
Optimatrix
Novel synthetic, reversible OVD for safe, simple application. Optimatrix is fully synthetic, preserves ocular volume and shape during surgery, and is removed easily with a cold saline wash. Cold‑saline dissolution prevents residue‑driven inflammation and cuts reliance on animal‑derived materials.
•
1. Ethical Supply Security
Fully synthetic with zero animal‑derived components, ensuring ethical sourcing and superior animal‑welfare credentials. That guarantees supply‑chain security for partners and removes ethical and regulatory exposure.
•
2. Scale Fast, Cut Costs
Low COGS, scalable production and tight sterility/endotoxin control deliver commercially compelling unit economics—reliable margins and predictable supply at scale.
•
3. Rapid Removal via Dissolution
Cold‑saline instantly dissolves the product, enabling fast, effortless removal right after surgery—no scraping, no residue, and minimal OR time.
Franchise 002 Tissue Spacing
Tutelix
Tutelix is intended for use as a spacer to reduce side effects to surrounding tissue during radiation therapy to treat prostate cancer. It is easily injected and is gradually resorbed by the body and excreted over time.
•
1. Procedure Optionality
Clinicians can apply it at their pace—no chemical cure, no time pressure—using one or multiple units as needed.
•
2. Stable and Simple to Adjust
The hydrogel is smooth, flowable and can be immediately reversed with cold-saline. The hydrogel is stable for 6 months and breaks down to non-toxic components and bioresorbs
•
3. Visibility Drives Precise Radiotherapy
The hydrogel is visible during the surgery under ultrasound so clinicians can see where they are deploying the product. It remains visible and stable for accurate radiation therapy
Franchise 002 Tissue Spacing
Optimatrix
TegenEOS mixes with human derived bone grafts to form flowable formulations with lower graft content; reducing the dependency on human donors while allowing novel minimally invasive applications in foot and ankle trauma and general orthopaedic surgeries.
•
1. Ethical Supply Security
Fully synthetic with zero animal‑derived components, ensuring ethical sourcing and superior animal‑welfare credentials. That guarantees supply‑chain security for partners and removes ethical and regulatory exposure.
•
2. Scale Fast, Cut Costs
Low COGS, scalable production and tight sterility/endotoxin control deliver commercially compelling unit economics—reliable margins and predictable supply at scale.
•
3. Rapid Removal via Dissolution
Cold‑saline instantly dissolves the product, enabling fast, effortless removal right after surgery—no scraping, no residue, and minimal OR time.
Franchise 002 Tissue Spacing
Tutelix
Tutelix is intended for use as a spacer to reduce side effects to surrounding tissue during radiation therapy to treat prostate cancer. It is easily injected and is gradually resorbed by the body and excreted over time.
•
1. Procedure Optionality
Clinicians can apply it at their pace—no chemical cure, no time pressure—using one or multiple units as needed.
•
2. Stable and Simple to Adjust
The hydrogel is smooth, flowable and can be immediately reversed with cold-saline. The hydrogel is stable for 6 months and breaks down to non-toxic components and bioresorbs
•
3. Visibility Drives Precise Radiotherapy
The hydrogel is visible during the surgery under ultrasound so clinicians can see where they are deploying the product. It remains visible and stable for accurate radiation therapy
Franchise 002 Tissue Spacing
Optimatrix
TegenEOS mixes with human derived bone grafts to form flowable formulations with lower graft content; reducing the dependency on human donors while allowing novel minimally invasive applications in foot and ankle trauma and general orthopaedic surgeries.
•
1. Ethical Supply Security
Fully synthetic with zero animal‑derived components, ensuring ethical sourcing and superior animal‑welfare credentials. That guarantees supply‑chain security for partners and removes ethical and regulatory exposure.
•
2. Scale Fast, Cut Costs
Low COGS, scalable production and tight sterility/endotoxin control deliver commercially compelling unit economics—reliable margins and predictable supply at scale.
•
3. Rapid Removal via Dissolution
Cold‑saline instantly dissolves the product, enabling fast, effortless removal right after surgery—no scraping, no residue, and minimal OR time.
Franchise 002 Tissue Spacing
Tutelix
Tutelix is intended for use as a spacer to reduce side effects to surrounding tissue during radiation therapy to treat prostate cancer. It is easily injected and is gradually resorbed by the body and excreted over time.
•
1. Procedure Optionality
Clinicians can apply it at their pace—no chemical cure, no time pressure—using one or multiple units as needed.
•
2. Stable and Simple to Adjust
The hydrogel is smooth, flowable and can be immediately reversed with cold-saline. The hydrogel is stable for 6 months and breaks down to non-toxic components and bioresorbs
•
3. Visibility Drives Precise Radiotherapy
The hydrogel is visible during the surgery under ultrasound so clinicians can see where they are deploying the product. It remains visible and stable for accurate radiation therapy
Franchise 002 Tissue Spacing
Optimatrix
TegenEOS mixes with human derived bone grafts to form flowable formulations with lower graft content; reducing the dependency on human donors while allowing novel minimally invasive applications in foot and ankle trauma and general orthopaedic surgeries.
•
1. Ethical Supply Security
Fully synthetic with zero animal‑derived components, ensuring ethical sourcing and superior animal‑welfare credentials. That guarantees supply‑chain security for partners and removes ethical and regulatory exposure.
•
2. Scale Fast, Cut Costs
Low COGS, scalable production and tight sterility/endotoxin control deliver commercially compelling unit economics—reliable margins and predictable supply at scale.
•
3. Rapid Removal via Dissolution
Cold‑saline instantly dissolves the product, enabling fast, effortless removal right after surgery—no scraping, no residue, and minimal OR time.
Franchise 003 Tissue Healing
TetraDerm
A flowable intraoperative matrix that cushions tissues, reduces mechanical tension and dead space, and lowers scar formation across reconstructions, arthroplasty, cesarean sections, and other surgeries
•
1. Universal, Thermo‑Triggered Gelation
A flowable dermal matrix that gels at body temperature—no light, no chemicals—making it universally deployable across clinical settings, safe and easy to use with no special equipment required,
•
2. Biomimetic Scaffold for Natural Healing
The mimetic of the hydrogel allows biological integration of the hydrogel within the host tissue and provides a physical scaffold for cellular regeneration and skin remodelling.
•
3. Cushioning to Minimise Scarring
Mechanical tension fuels myofibroblast activation and scarring; our matrix cushions tissues and fills dead space to cut tension and prevent scar formation.
Franchise 003 Tissue Healing
TetraDerm
A flowable intraoperative matrix that cushions tissues, reduces mechanical tension and dead space, and lowers scar formation across reconstructions, arthroplasty, cesarean sections, and other surgeries
•
1. Universal, Thermo‑Triggered Gelation
A flowable dermal matrix that gels at body temperature—no light, no chemicals—making it universally deployable across clinical settings, safe and easy to use with no special equipment required,
•
2. Biomimetic Scaffold for Natural Healing
The mimetic of the hydrogel allows biological integration of the hydrogel within the host tissue and provides a physical scaffold for cellular regeneration and skin remodelling.
•
3. Cushioning to Minimise Scarring
Mechanical tension fuels myofibroblast activation and scarring; our matrix cushions tissues and fills dead space to cut tension and prevent scar formation.
Franchise 003 Tissue Healing
TetraDerm
A flowable intraoperative matrix that cushions tissues, reduces mechanical tension and dead space, and lowers scar formation across reconstructions, arthroplasty, cesarean sections, and other surgeries
•
1. Universal, Thermo‑Triggered Gelation
A flowable dermal matrix that gels at body temperature—no light, no chemicals—making it universally deployable across clinical settings, safe and easy to use with no special equipment required,
•
2. Biomimetic Scaffold for Natural Healing
The mimetic of the hydrogel allows biological integration of the hydrogel within the host tissue and provides a physical scaffold for cellular regeneration and skin remodelling.
•
3. Cushioning to Minimise Scarring
Mechanical tension fuels myofibroblast activation and scarring; our matrix cushions tissues and fills dead space to cut tension and prevent scar formation.
Franchise 004 Precision Medicine
STEPP
STEPP is an intranasal delivery system derived from our Tetramatrix platform. It is a mucoadhesive aerosol, engineered with controlled droplet size and plume shape to maximise nasal mucosal deposition and minimise nose and throat runoff. Its sticky formulation prolongs residence time, enhances transmucosal absorption, and delivers improved bioavailability with precise, reproducible dosing.
•
1. Improved Stability
Protects the loaded drug pre-dose, cutting denaturation risk and preserving potency through storage and delivery.
•
2. Modular Predictability
Mucoadhesive deposition and extended residence time make it modular for a wide range of active compounds to drive higher systemic uptake and more predictable exposure.
•
3. Commercial Scalability
Precise dosing, reduced variability, and robust stability de-risk clinical development and accelerate market adoption.
Franchise 004 Precision Medicine
STEPP
STEPP is an intranasal delivery system derived from our Tetramatrix platform. It is a mucoadhesive aerosol, engineered with controlled droplet size and plume shape to maximise nasal mucosal deposition and minimise nose and throat runoff. Its sticky formulation prolongs residence time, enhances transmucosal absorption, and delivers improved bioavailability with precise, reproducible dosing.
•
1. Improved Stability
Protects the loaded drug pre-dose, cutting denaturation risk and preserving potency through storage and delivery.
•
2. Modular Predictability
Mucoadhesive deposition and extended residence time make it modular for a wide range of active compounds to drive higher systemic uptake and more predictable exposure.
•
3. Commercial Scalability
Precise dosing, reduced variability, and robust stability de-risk clinical development and accelerate market adoption.
Franchise 004 Precision Medicine
STEPP
STEPP is an intranasal delivery system derived from our Tetramatrix platform. It is a mucoadhesive aerosol, engineered with controlled droplet size and plume shape to maximise nasal mucosal deposition and minimise nose and throat runoff. Its sticky formulation prolongs residence time, enhances transmucosal absorption, and delivers improved bioavailability with precise, reproducible dosing.
•
1. Improved Stability
Protects the loaded drug pre-dose, cutting denaturation risk and preserving potency through storage and delivery.
•
2. Modular Predictability
Mucoadhesive deposition and extended residence time make it modular for a wide range of active compounds to drive higher systemic uptake and more predictable exposure.
•
3. Commercial Scalability
Precise dosing, reduced variability, and robust stability de-risk clinical development and accelerate market adoption.
If you’re exploring a clinical application partnership, share your intended use-case and evaluation stage and we’ll respond with clear next steps.
If you’re exploring a clinical application partnership, share your intended use-case and evaluation stage and we’ll respond with clear next steps.
If you’re exploring a clinical application partnership, share your intended use-case and evaluation stage and we’ll respond with clear next steps.
THE OVERVIEW
© 2026 Tetratherix Limited
© 2026 Tetratherix Limited